Oestrogen Metabolism
Estrobolome is the microbiome in the gut that manages the metabolism of oestrogen in the body.
Oestrogen is produced in the ovaries and circulated to tissues and organs around the body. This is known as ‘active’ oestrogen.
Active oestrogen eventually gets filtered through the liver which then ‘deactivates’ it and sends it to the gut.
When the body’s estrobolome is balanced and healthy, the deactivated oestrogen is excreted via the stools and leaves the body.
This process keeps oestrogen levels balanced with progesterone and other hormones.
If your estrobolome is unbalanced, known as dysbiosis, certain bacteria can reactivate inactive oestrogen in your gut by producing an enzyme called beta-glucuronidase. If there is too much of this bacteria present, oestrogen is recirculated causing more oestrogen instead of reducing it, resulting in Oestrogen Dominance.
Oestrogen dominance is a common issue among women who suffer heavier, painful periods. Other symptoms include:
• Irregular periods
• Water retention
• Breast swelling and tenderness
• Headaches and migraines
• Fibrocystic breast changes
• Weight gain
• Hair loss
• PMS symptoms
• Low thyroid hormone
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